Invitrogen™ GRK5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596262

Catalog No. PIPA596262

Description

Immunogen sequence: LGCLIYEMIE GQSPFRGRKE KVKREEVDRR VLETEEVYSH KFSEEAKSIC KMLLTKDAKQ RLGCQEEGAA EVKRHPFFRN MNFKRLEAGM LDPPFVPDPR AVYCKDVLDI EQFSTVKGVN LDHTDDDFYS KFSTGSVSIP WQNEMIETEC FKELNVFGPN GTLPPDLNRN HPPEPPKKGL LQRLFKRQHQ NNSKSSPSSK TSFNHHINSN HVSSNSTGSS; Positive Samples: A-549, U-251MG, HepG2, 293T, HT-1080, Mouse liver, Mouse lung; Cellular Location: Cell membrane, Cytoplasm, Nucleus, Peripheral membrane protein.

GRK5 is a serine/threonine kinase that regulates the activity of a variety of G protein-coupled receptors and the motility of polymorphonuclear leukocytes. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes.

Specifications

• Antigen: GRK5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRK5
• Gene Alias: 1200003L19Rik; Alpha-CP4; AlphaCP-4; FP2025; G protein-coupled receptor kinase 5; G protein-coupled receptor kinase GRK5; Gprk5; GRK; Grk5; GRK5 protein kinase; GRK-pan; Pan-GRK; Pcbp4; poly(rC) binding protein 4; poly(rC)-binding protein 4
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11476, 14773, 236300, 2869, 59075, 59092
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.96 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P34947, Q62833, Q8VEB1
• Gene Symbols: GRK5
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 371-590 of human GRK5 (NP_0052991).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG