GRM4 Mouse anti-Human, Clone: OTI6D1, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF810384

Catalog No. 50-167-0048

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The Metabotropic Glutamate Receptor mGluR4/GRM4 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties.

Specifications

• Antigen: GRM4
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: GRM4
• Gene Alias: GPRC1D, MGLUR4, mGlu4
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2914
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI6D1
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q14833
• Gene Symbols: GRM4
• Immunogen: Human recombit protein fragment corresponding to amino acids 126-407 of human GRM4 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a