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Invitrogen™ Growth Hormone Polyclonal Antibody
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Catalog No. PIPA579308
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100 μg
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Catalog No. Quantity
PIPA579308 100 μg
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Catalog No. PIPA579308 Supplier Invitrogen™ Supplier No. PA579308
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - IHC: rat brain tissue.

Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The GH1 gene, along with 4 additional related genes, is located at the growth hormone locus on chromosome 17. The five genes share a remarkably high degree of sequence identity. Alternative splicing results in 5 isoforms ranging from approximately 19 kDa to 24 kDa. HGH is produced by the somatotroph cells in the pituitary. It acts through binding to membrane receptors that belong to the cytokine receptor subfamily. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Mutations or deletions in the gene lead to growth hormone deficiency and short stature.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Growth Hormone
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and no preservative
Gene Gh1
Gene Accession No. P01244
Gene Alias dog growth hormone; GH; Gh1; GHB1; GHB5; GHN; GH-N; Growth hormone; growth hormone 1; growth hormone 12; growth hormone B1; growth hormone B5; growth hormone precursor; HGH; hGH-N; IGHD1B; pituitary growth hormone; rHGH; RNGHGP; Somatotropin
Gene Symbols Gh1
Host Species Rabbit
Immunogen E. coli-derived rat GH recombinant protein (Position: F27-F216).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24391
Target Species Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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