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Invitrogen™ GRPEL2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA554723

Catalog No. PIPA554723


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Description

Description

Immunogen sequence: VRSLWAGRLR VQRLLAWSAA WESKGWPLPF STATQRTAGE DCRSEDPPDE LGPPLAERAL RVKAVKLEKE VQDLTVRYQR AIADCENIRR RTQRCVEDAK IFGIQSFCKD LVE Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 83%.

GRPEL2 (GrpE Like 2, Mitochondrial) is a Protein Coding gene. Among its related pathways are Mitochondrial protein import and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and chaperone binding. An important paralog of this gene is GRPEL1. Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

GRPEL2
Polyclonal
Unconjugated
GRPEL2
actin filament-associated protein 1-like 1; Afap1l1; AFAP1-like protein 1; GrpE like 2, mitochondrial; grpE protein homolog 2, mitochondrial; Grpel2; GrpE-like 2, mitochondrial; Mt-GrpE#2; Mt-grpel2
Rabbit
Antigen Affinity Chromatography
RUO
134266, 17714, 688777
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
0.2 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
O88396, Q8TAA5
GRPEL2
Recombinant protein corresponding to Human GRPEL2. Recombinant protein control fragment (Product #RP-91013).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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