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Invitrogen™ GRPR Polyclonal Antibody
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Catalog No. PIPA526791
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400 μL
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PIPA526791 400 μL
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Catalog No. PIPA526791 Supplier Invitrogen™ Supplier No. PA526791
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Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with mouse and rat based on sequence homology.

Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GRPR
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1.8 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene GRPR
Gene Accession No. P30550
Gene Alias BB2; BB2R; bombesin receptor 2; gastrin releasing peptide receptor; gastrin-releasing peptide receptor; GRP receptor; GRP-preferring bombesin receptor; GRPR; GRP-R
Gene Symbols GRPR
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 123-152 amino acids from the central region of human GRPR.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2925
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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