Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Imidazopyrimidines
  7. GS 6201, Tocris Bioscience™

GS 6201, Tocris Bioscience™

Catalog No. 472750
Click to view available options
Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective A2B antagonist

Selective antagonist of adenosine A2B receptors (Ki values are 22, 1070, 1940 and 3280 nM for human A2B, A3, A1 and A2A receptors respectively). Attenuates allergen-, NECA- and AMP-induced airway reactivity in an allergic mouse model of asthma. Also shown to attenuate the inflammatory response during acute myocardial infarction in mice; reduces caspase-1 activity in the heart.

Chemical Identifiers

CAS 752222-83-6
Molecular Formula C21H21F3N6O2
Molecular Weight (g/mol) 446.434
InChI Key KOYXXLLNCXWUNF-UHFFFAOYSA-N
Synonym unii-67ckv7x08g, 3-ethyl-3,9-dihydro-1-propyl-8-1-3-trifluoromethyl phenyl methyl-1h-pyrazol-4-yl-1h-purine-2,6-dione, kinome_3621, d0g4cf, 3-ethyl-1-propyl-8-1-3-trifluoromethyl phenyl methyl pyrazol-4-yl-7h-purine-2,6-dione, 1h-purine-2,6-dione, 3-ethyl-3,9-dihydro-1-propyl-8-1-3-trifluoromethyl phenyl methyl-1h-pyrazol-4-yl, 3-ethyl-1-propyl-8-1-3-trifluoromethyl benzyl-1h-pyrazol-4-yl-1h-purine-2,6 3h,7h-dione, 3-ethyl-1-propyl-8-1-3-trifluoromethylbenzyl-1h-pyrazol-4-yl-3,7-dihydropurine-2,6-dione, 3-ethyl-1-propyl-8-1-3-trifluoromethyl phenyl methyl pyrazol-4-yl-9h-purine-2,6-dione, 8-1-3-trifluoromethyl benzyl-1h-pyrazol-4-yl-3-ethyl-1-propyl-1h-purine-2,6 3h,7h-dione
PubChem CID 11270783
IUPAC Name 3-ethyl-1-propyl-8-[1-[[3-(trifluoromethyl)phenyl]methyl]pyrazol-4-yl]-7H-purine-2,6-dione
SMILES CCCN1C(=O)C2=C(N=C(N2)C3=CN(N=C3)CC4=CC(=CC=C4)C(F)(F)F)N(C1=O)CC

Specifications

Quantity 50 mg
Formula Weight 446.43
Percent Purity >99%
Chemical Name or Material GS 6201

Safety and Handling

Recommended Storage Store at -20°C
Provide Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.