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Invitrogen™ GSC2 Polyclonal Antibody
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Catalog No. PIPA560198
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100 μL
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PIPA560198 100 μL
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Catalog No. PIPA560198 Supplier Invitrogen™ Supplier No. PA560198
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PFSIEHILSS LPERSLPARA ACPPQPAGRQ SPAKPEEP Highest antigen sequence identity to the following orthologs: Mouse - 63%, Rat - 68%.

Goosecoidlike (GSCL) resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology.Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology. The gene is expressed in a limited number of adult tissues, as well as in early human development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GSC2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene GSC2
Gene Accession No. O15499
Gene Alias 4930568H22Rik; goosecoid homebox 2; goosecoid homeobox 2; GSC2; GSC-2; GSCL; GSC-L; homeobox protein goosecoid-2; Homeobox protein goosecoid-like; LOW QUALITY PROTEIN: homeobox protein goosecoid-2
Gene Symbols GSC2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human GSC2. Recombinant protein control fragment (Product #RP-99858).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2928
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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