Invitrogen™ GSC2 Polyclonal Antibody

Catalog No.	Quantity
PIPA5101060	100 μL

Catalog No. PIPA5101060

Supplier: Invitrogen™ PA5101060

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total GSC2.

Goosecoidlike (GSCL) resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology.Goosecoidlike (GSCL), a homeodomain-containing gene, resides in the critical region for VCFS/DGS on 22q11. Velocardiofacial syndrome (VCFS) is a developmental disorder characterized by conotruncal heart defects, craniofacial anomalies, and learning disabilities. VCFS is phenotypically related to DiGeorge syndrome (DGS) and both syndromes are associated with hemizygous 22q11 deletions. Because many of the tissues and structures affected in VCFS/DGS derive from the pharyngeal arches of the developing embryo, it is believed that haploinsufficiency of a gene involved in embryonic development may be responsible for its etiology. The gene is expressed in a limited number of adult tissues, as well as in early human development.

Specifications

• Antigen: GSC2
• Applications: Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: GSC2
• Gene Accession No.: O15499, P56916
• Gene Alias: 4930568H22Rik; goosecoid homebox 2; goosecoid homeobox 2; GSC2; GSC-2; GSCL; GSC-L; homeobox protein goosecoid-2; Homeobox protein goosecoid-like; LOW QUALITY PROTEIN: homeobox protein goosecoid-2
• Gene Symbols: GSC2
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human GSC2(Accession O15499), corresponding to amino acid residues E142-R192.
• Purification Method: Affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 195333, 2928
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG