Invitrogen™ GSDMC Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA555303

Catalog No. PIPA555303

Description

Immunogen sequence: LPVGRIEEPF WQNFKHLQEE VFQKIKTLAQ LSKDVQDVMF YSILAMLRDR GALQDLMNML ELDSSGHLDG PGGAILKKLQ QDSNHAWFNP KDP Highest antigen sequence identity to the following orthologs: Mouse - 54%, Rat - 53%.

The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown (Probable). [UniProt].

Specifications

• Antigen: GSDMC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GSDMC
• Gene Alias: gasdermin C; gasdermin C1; gasdermin-C; Gasdermin-C1; Gsdmc; Gsdmc1; melanoma-derived leucine zipper, extra-nuclear factor; melanoma-derived leucine zipper-containing extranuclear factor; MLZE; mMLZE
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56169
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9BYG8
• Gene Symbols: GSDMC
• Immunogen: Recombinant protein corresponding to Human GSDMC. Recombinant protein control fragment (Product #RP-93820).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG