Invitrogen™ GSDMC Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101660

Catalog No. PIPA5101660

Description

Antibody detects endogenous levels of total GSDMC.

The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown (Probable). [UniProt].

Specifications

• Antigen: GSDMC
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GSDMC
• Gene Alias: gasdermin C; gasdermin C1; gasdermin-C; Gasdermin-C1; Gsdmc; Gsdmc1; melanoma-derived leucine zipper, extra-nuclear factor; melanoma-derived leucine zipper-containing extranuclear factor; MLZE; mMLZE
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 56169
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9BYG8
• Gene Symbols: GSDMC
• Immunogen: A synthesized peptide derived from human GSDMC(Accession Q9BYG8), corresponding to amino acid residues E108-V158.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov