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GSK 1059615, Tocris Bioscience™

Catalog No. 402610
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Catalog No. Quantity
40-261-0 10 mg
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Catalog No. 40-261-0 Supplier R&D Systems Supplier No. 4026/10
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Description

Potent PI 3-kinase inhibitor

Potent inhibitor of PI 3-kinase α (PI3Kα) (IC50 = 2 nM). Inhibits proliferation in BT474 cells and attenuates MAPK signaling.

Chemical Identifiers

CAS 958852-01-2
Molecular Formula C18H11N3O2S
Molecular Weight (g/mol) 333.365
InChI Key QDITZBLZQQZVEE-YBEGLDIGSA-N
Synonym z-5-4-pyridin-4-yl quinolin-6-yl methylene thiazolidine-2,4-dione, 5-4-4-pyridinyl-6-quinolinyl methylene-2,4-thiazolidenedione, 5-4-pyridin-4-yl quinolin-6-yl methylene-1,3-thiazolidine-2,4-dione, 5z-5-4-pyridin-4-ylquinolin-6-yl methylidene-1,3-thiazolidine-2,4-dione, 5z-5-4-pyridin-4-yl quinolin-6-yl methylidene-1,3-thiazolidine-2,4-dione, 5-z-4-4-pyridyl-6-quinolyl methylene thiazolidine-2,4-dione, 5z-5-4-4-pyridinyl-6-quinolinyl methylidene-1,3-thiazolidine-2,4-dione
PubChem CID 23582824
IUPAC Name (5Z)-5-[(4-pyridin-4-ylquinolin-6-yl)methylidene]-1,3-thiazolidine-2,4-dione
SMILES C1=CC2=NC=CC(=C2C=C1C=C3C(=O)NC(=O)S3)C4=CC=NC=C4

Specifications

Quantity 10 mg
Formula Weight 333.36
Percent Purity >98%
Chemical Name or Material GSK 1059615

Safety and Handling

Recommended Storage Store at +4°C
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