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R&D Systems™ GSK 2606414
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Catalog No. 510750 Shop All Novus Products
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Catalog No. Quantity
51-075-0 50 mg
51-071-0 10 mg
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Catalog No. 51-075-0 Supplier R&D Systems™ Supplier No. 5107/50

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Description

A Tocris product, part of R&D Systems. Potent and selective PERK inhibitor; orally bioavailable

GSK 2606414 is a potent and selective protein kinase R-like ER kinase (PERK) inhibitor (IC50 = 0.4 nM). Exhibits >1000-fold selectivity for PERK over HR1 and PKR. Inhibits thapsigargin-induced PERK phosphorylation in lung carcinoma A549 cells. Attenuates subcutaneous pancreatic human tumor xenograft growth in mice. Orally bioavailable.

Specifications

Quantity 50 mg
Product Line Tocris
Product Type GSK 2606414
Purity >99%
Molecular Weight (g/mol) 451.44
Inhibitors GSK 2606414

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