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  5. Tocris Bioscience™ GSK 2795039

Tocris Bioscience™ GSK 2795039
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Catalog No. 68485
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Quantity:
5 mg
25 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

NADPH oxidase 2 (NOX2) inhibitor

GSK 2795039 is a NADPH oxidase 2 (NOX2) inhibitor (pIC50 value is 5.5 to 6.5, depending on assay performed), which displays selectivity for NOX2 other NOX isoforms, xanthine oxidase and eNOS. GSK 2795039 inhibits reactive oxygen species (ROS) in cellular assays, and displays efficacy in rodent models of paw inflammation and acute pancreatitis.

Specifications

Chemical Name or Material N-[3-(2,3-Dihydro-1-methyl-1 H-indol-6-yl)-1-(1-methylethyl)-1 H-pyrrolo[2,3-b]pyridin-4-yl]-1-methyl-1 H-pyrazole-3-sulfonamide
CAS 1415925-18-6
Quantity 5 mg
Target NADPH Oxidase Inhibitors
Molecular Formula C23H26N6O2S
Purity 0.98
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