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Tocris Bioscience™ GSK 2879552
SDP

Catalog No. 812810 Shop All R&D Systems Products
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81-281-0 10 mg
81-285-0 50 mg
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Catalog No. 81-281-0 Supplier Tocris Bioscience™ Supplier No. 8128/10
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Description

Lysine-Specific Demethylase 1 (LSD1) inhibitor

GSK 2879552 is a selective lysine-specific demethylase 1 (LSD1) inhibitor. When combined with other small molecules (EPZ-5676, N-methyl-d-aspartate and Bay K 8644), GSK 2879552 accelerates maturation of human pluripotent stem cell-derived neurons. GSK 2879552 inhibits the growth of small cell lung carcinoma (SCLC) and AML lines. In vivo, GSK 2879552 (1.5 mg/kg, p.o.) demonstrates tumor growth inhibition in SCLC xenograph mouse models.

Specifications

Chemical Name or Material 4-[[4-[[[(1R,2S)-2-Phenylcyclopropyl]amino]methyl]-1-piperidinyl]methyl]benzoic acid dihydrochloride
CAS 1902123-72-1
Quantity 10 mg
Target Histone Demethylase Inhibitors
Molecular Formula C23H28N2O2.2HCl
Purity 98%
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