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Tocris Bioscience™ GSK 343

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Quantity:
50 mg
Description
GSK 343 is a potent and selective SAM-competitive EZH2 inhibitor (IC50 = 4 nM), that exhibits >60 fold selectivity for EZH2 over EZH1 and a range of other methyltransferases. GSK 343 decreases H3K27me3 levels in breast cancer cells and inhibits proliferation of prostate cancer cell lines in vitro.
Specifications
Specifications
Chemical Name or Material | N-[(1,2-Dihydro-6-methyl-2-oxo-4-propyl-3-pyridinyl)methyl]-1-(1-methylethyl)-6-[2-(4-methyl-1-piperazinyl)-4-pyridinyl]-1H-indazole-4-carboxamide |
CAS | 1346704-33-3 |
Assay Percent Range | >98% |
Quantity | 50 mg |
Molecular Formula | C31H39N7O2 |
Formula Weight | Observed MW: 541.69 |
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