Tocris Bioscience™ GSK 4112

Description

Selective Rev-Erbα agonist

GSK 4112 is a selective Rev-Erbα agonist (EC50 = 250 nM). Enhances recruitment of nuclear receptor co-repressor (NCoR) peptide to Rev-Erbα; causes acute suppression of Bmal1 gene transcription. Induces phase shifts in the circadian clock.

Specifications

• Quantity: 10 mg
• Product Type: GSK 4112
• Purity: >98%
• Molecular Weight (g/mol): 396.89
• Inhibitors: GSK 4112

For Research Use Only