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  5. Tocris Bioscience™ GSK J4

Tocris Bioscience™ GSK J4
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Catalog No. 459450
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Catalog No. Quantity
45-945-0 50 mg
45-941-0 10 mg
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Catalog No. 45-945-0 Supplier Tocris Bioscience™ Supplier No. 4594/50
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Description

Histone KDM inhibitor; cell permeable

Histone lysine demethylase (KDM) inhibitor; blocks demethylation of histone H3K27. Attenuates lipopolysaccharide (LPS)-induced proinflammatory cytokine production in primary human macrophages (IC50 = 9 μM for the inhibition of TNFα release). Cell permeable. Ethyl ester derivative of GSK J1 .

Negative Control also available.

Chemical Identifiers

CAS 1373423-53-0
Molecular Formula C24H27N5O2

Specifications

Quantity 50 mg
Formula Weight 417.5
Purity >99%
Molecular Weight (g/mol) 417.513
Chemical Name or Material GSK J4

Safety and Handling

Recommended Storage Store at Room Temperature
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