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Invitrogen™ GSK3B Monoclonal Antibody (21A)

Catalog No. 01670355
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100 μg
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Catalog No. Quantity
01-670-355 100 μg
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Catalog No. 01-670-355 Supplier Invitrogen™ Supplier No. MA17621
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Description

Mouse Monoclonal Antibody

MA1-7621 detects GSK3 Beta from human, rat, and Xenopus laevis samples. MA1-7621 has been successfully used in ELISA, Western blot, Flow cytometry, Immunoprecipitation and Immunohistochemistry procedures. The MA1-7621 immunogen is a purified recombinant Xenopus laevis protein. Store at 4ºC short term. For extended storage, keep at -80ºC.

GSK3B is a proline-directed serine/threonine protein kinase involved in energy metabolism, neuronal cell development and body pattern formation. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. GSK3B is a critical component of the Wnt/beta-catenin signaling pathway, and its activity results in the inhibition of Wnt signaling by mediating the degradation of beta-catenin. GSK3B is also involved in the Hedgehog, Notch, and insulin signaling pathways.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GSK3B
Applications ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Monoclonal
Clone 21A
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.01% sodium azide; pH 7.2
Gene GSK3B
Gene Accession No. P18266, P49841, Q91757
Gene Alias 7330414F15Rik; 8430431H08Rik; C86142; EC 2.7.11.26; FA; Factor A; fb68h05; fk80d11; glycogen synthase kinase 3; glycogen synthase kinase 3 beta; glycogen synthase kinase 3 beta L homeolog; glycogen synthase kinase 3 beta variant 1; glycogen synthase kinase 3 beta variant 2; glycogen synthase kinase 3 beta variant 3; glycogen synthase kinase 3 beta variant 4; glycogen synthase kinase 3 beta variant 5; glycogen synthase kinase 3 beta, genome duplicate a; glycogen synthase kinase-3 beta; glycogen synthase kinase-3 beta splice variant X1; glycogen synthase kinase-3 beta splice variant X2; glycogen synthase kinase-3 beta splice variant X3; GSK 3 beta; GSK 3B; gsk3; GSK-3; GSK3 beta; GSK-3 beta; GSK-3 beta GSK3B; GSK-3[b]; Gsk3b; GSK-3b; gsk3b.L; gsk3ba; gsk3beta; GSK-3beta; gsk3-beta; GSK3beta isoform; intracellular kinase; pp37; serine/threonine-protein kinase GSK3B; wu:fb68h05; wu:fk80d11; XELAEV_180112401mg; xgsk-3; Xgsk-3 protein
Gene Symbols GSK3B, gsk3b.L
Host Species Mouse
Immunogen Purified recombinant Xenopus laevis protein.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2932, 399097, 84027
Target Species Human, Rat, Frog
Content And Storage 4°C short term, -80°C long term
Product Type Antibody
Form Liquid
Isotype IgG2a
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