Invitrogen™ GSPT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA545624

Catalog No. PIPA545624

Description

Peptide sequence: AGGRAAPVES SQEEQSLCEG SNSAVSMELS EPIENGETEM SPEESWEHKE Sequence homology: Cow: 93%; Dog: 87%; Human: 100%; Pig: 87%; Rabbit: 100%; Rat: 93%.

eRF3a (eukaryotic peptide chain release factor subunit 3a), also known as GSPT1 (G1 to S phase transition 1), is a 499 amino acid protein that belongs to the GTP-binding elongation factor family and is involved in the regulation of cell growth, specifically via control of translation termination. Human eRF3a shares 94% sequence identity with its mouse counterpart, suggesting a conserved function between species. The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth.

Specifications

• Antigen: GSPT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GSPT1
• Gene Alias: 551G9.2; AI314175; AI326449; AV307676; C79774; ELF; ERF3A; ETF3A; Eukaryotic peptide chain release factor GTP-binding subunit ERF3A; eukaryotic peptide chain release factor subunit 3a; eukaryotic polypeptide chain release factor 3; G1 to phase transition 1; G1 to S phase transition 1; G1 to S phase transition protein 1; G1 to S phase transition protein 1 homolog; G1st; G1-to-S phase transition 1; G1-to-S transition GTP binding protein; GSPT1; GST1; Gst-1; guanine nucleotide regulatory protein
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2935
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: P15170
• Gene Symbols: GSPT1
• Immunogen: Synthetic peptide directed towards the N-terminal of human GSPT1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov