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Invitrogen™ GSR Polyclonal Antibody
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Catalog No. PIPA588332
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100 μL
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PIPA588332 100 μL
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Catalog No. PIPA588332 Supplier Invitrogen™ Supplier No. PA588332
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MISTNCTEEL ENAGVEVLKF SQVKEVKKTL SGLEVSMVTA VPGRLPVMTM IPDVDCLLWA IGRVPNTKDL SLNKLGIQTD DKGHIIVDEF QNTNVKGIYA VGDVCGKALL TPVAIAAGRK LAHRLFEYKE DSKLDYNNIP TVVFSHPPIG TVGLTEDEAI HKYGIENVKT YSTSFTPMYH AVTKRKTKCV MKMVCANKEE KVVGIHMQGL GCDEMLQGFA VAVKMGATKA DFDNTVAIHP TSSEELVTLR; Positive Samples: LO2, HeLa, A-549, Jurkat, Mouse brain, Mouse heart, Mouse kidney; Cellular Location: Cytoplasm, Mitochondrion.

This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GSR
Applications ELISA, Western Blot, Western Blot
Classification Polyclonal
Concentration 0.42 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Gsr
Gene Accession No. P00390, P47791
Gene Alias AI325518; D8Ertd238e; epididymis luminal protein 75; epididymis secretory sperm binding protein Li 122m; GLUR; glutathione reductase; glutathione reductase 1; glutathione reductase, mitochondrial; glutathione S-reductase; glutathione-disulfide reductase; GR; Gr1; Gr-1; GRase; GRD1; GSR; HEL-75; HEL-S-122m; hypothetical protein LOC553575; zgc:110010
Gene Symbols Gsr
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 273-522 of human GSR (NP_0006282).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14782, 2936
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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