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Invitrogen™ GSTA3/GSTA5 Polyclonal Antibody
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Catalog No. PIPA5142682
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100 μg
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PIPA5142682 100 μg
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Catalog No. PIPA5142682 Supplier Invitrogen™ Supplier No. PA5142682
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Description

Goat Polyclonal Antibody

Additional Information: This antibody is expected to cross-react to the homologous Mouse protein Gsta3. This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000.

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008].
TRUSTED_SUSTAINABILITY

Specifications

Antigen GSTA3/GSTA5
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene GSTA3
Gene Accession No. P04904, P30115, P46418
Gene Symbols GSTA3, GSTA5
Host Species Goat
Immunogen Peptide with sequence C-EMDPGIVDNFPLLK.
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100042314, 14859, 494499, 494500
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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