Invitrogen™ GSTM3 Monoclonal Antibody (1G1F1)

Catalog No.	Quantity
FEMA550282	100 μL

Catalog No. FEMA550282 Supplier Invitrogen™ Supplier No. MA550282

Description

Mouse Monoclonal Antibody

GSTM3 Monoclonal Antibody for Western Blot, IHC (P), Flow, ELISA

Glutathione S-transferase M3 (brain), also known as GSTM3, is an enzyme which in humans is encoded by theGSTM3 gene. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13. 3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins.

Specifications

• Antigen: GSTM3
• Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 1G1F1
• Concentration: 2 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
• Gene: GSTM3
• Gene Accession No.: P21266
• Gene Alias: brain GST; brain type mu-glutathione S-transferase; Fsc2; glutathione S-alkyltransferase M3; glutathione S-aralkyltransferase M3; glutathione S-aryltransferase M3; glutathione S-transferase GT9.3; glutathione S-transferase M3 (brain); glutathione S-transferase Mu 3; glutathione S-transferase mu 3 (brain); glutathione S-transferase, mu 3; glutathione S-transferase, Mu-3; GST class-mu 3; GST5; GSTB; GSTM3; GSTM3-3; GTM3; hGSTM3-3; mGSTM5; S-(hydroxyalkyl)glutathione lyase M3
• Gene Symbols: GSTM3
• Host Species: Mouse
• Immunogen: Recombinant Human Glutathione S-transferase Mu 3 protein (1-225AA).
• Purification Method: Protein G
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2947
• Target Species: Human
• Content And Storage: -20°C or -80°C if preferred
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1