Invitrogen™ GSTM4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIPA5119149	Invitrogen™ PA5119149	200 μL
PIPA5121939	Invitrogen™ PA5121939	20 μL

Description

GSTM4 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Multiple transcript variants, each encoding a distinct protein isoform, have been identified.

Specifications

• Antigen: GSTM4
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Classification: Polyclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Rat
• Gene: GSTM4
• Gene Alias: 1110004G14Rik; glutathione S-alkyltransferase M4; glutathione S-aralkyltransferase M4; glutathione S-aryltransferase M4; glutathione S-transferase M4; glutathione S-transferase mu 3; glutathione S-transferase Mu 4; glutathione S-transferase, mu 4; glutathione-S-transferase, mu 4; GST class-mu 4; Gstb4; Gstb-4; GSTM4; GSTM4-4; GSTM7-7; GST-Mu2; GTM4; GTS-Mu2; S-(hydroxyalkyl)glutathione lyase M4; testis tissue sperm-binding protein Li 60n
• Gene Symbols: GSTM4
• Primary or Secondary: Primary
• Purification Method: Antigen affinity chromatography, Protein A

• Concentration: 0.5 mg/mL
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: 0
• Gene ID (Entrez): 499689
• Immunogen: Recombinant protein Glutathione S Transferase Mu 4.
• Product Type: Antibody