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Invitrogen™ GSTM5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5116635

Catalog No. PIPA5116635


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Description

Description

Positive Samples: Mouse heart, Mouse kidney, Mouse liver, Rat testis, Rat brain Immunogen sequence: LENQVMDNHM ELVRLCYDPD FEKLKPKYLE ELPEKLKLYS EFLGKRPWFA GDKITFVDFL AYDVLDMKRI FEPKCLDAFL NLKDFISRFE GLKKISAYMK SSQFLRGLLF GKSATWNSK.

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

GSTM5
Polyclonal
Unconjugated
GSTM5
fibrous sheath component 2; Fsc2; glutathione S-alkyltransferase M5; glutathione S-aralkyltransferase M5; glutathione S-aryltransferase M5; glutathione S-transferase M5; glutathione S-transferase Mu 5; glutathione S-transferase, mu 5; glutathione-S-transferase, mu 5; GST class-mu 5; Gstm3; GSTM5; GSTM5-5; GTM5; S-(hydroxyalkyl)glutathione lyase M5
Rabbit
Affinity chromatography
RUO
14866, 64352
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Western Blot
1.2 mg/mL
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
P48774, Q9Z1B2
GSTM5
A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of human GSTM5 (NP_0008422).
100 μL
Primary
Mouse, Rat
Antibody
IgG
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