Invitrogen™ GSTT1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588823

Catalog No. PIPA588823

Description

Positive Samples: HepG2, Mouse liver, Mouse kidney; Cellular Location: Cytoplasm Immunogen sequence: MGLELYLDLL SQPCRAVYIF AKKNDIPFEL RIVDLIKGQH LSDAFAQVNP LKKVPALKDG DFTLTESVAI LLYLTRKYKV PDYWYPQDLQ ARARVDEYLA WQHTTLRRSC LRALWHKVMF PVFLGEPVSP QTLAATLAEL DVTLQLLEDK FLQNKAFLTG PHISLADLVA ITELMHPVGA GCQVFEGRPK LATWRQRVEA AVGEDLFQEA HEVILKAKDF PPADPTIKQK LMPWVLAMIR.

Glutathione S-transferase (GST) theta 1 (GSTT1) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1 and GSTT2. The GSTT1 and GSTT2 share 55% amino acid sequence identity and both of them were claimed to have an important role in human carcinogenesis. The GSTT1 gene is located approximately 50kb away from the GSTT2 gene. The GSTT1 and GSTT2 genes have a similar structure, being composed of five exons with identical exon/intron boundaries.

Specifications

• Antigen: GSTT1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Gstt1
• Gene Alias: AI255817; Glutathione S-transferase 1 (theta); glutathione S-transferase 5; glutathione S-transferase theta 1; glutathione S-transferase theta-1; glutathione S-transferase, theta 1; glutathione transferase T1-1; GST 5-5; GST class-theta-1; GSTT1; Gstt1-1; GSTYRS; similar to Glutathione S-transferase theta 1 (GST class-theta 1) (Glutathione transferase T1-1)
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 14871, 25260, 2952
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.59 mg/mL
• Formulation: PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
• Gene Accession No.: P30711, Q01579, Q64471
• Gene Symbols: Gstt1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of GSTT1 (NP_0008442).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG