Invitrogen™ GTDC1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531858

Catalog No. PIPA531858

Description

Recommended positive controls: 293T, A431, Jurkat, Raji. Predicted reactivity: Mouse (93%), Xenopus laevis (81%), Chicken (85%), Rhesus Monkey (97%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The GTDC1 (Glycosyltransferase-Like Domain Containing 1) gene encodes a protein that is hypothesized to function as a glycosyltransferase. This gene has been implicated in several crucial biological processes, particularly in the nervous system. The GTDC1 cDNA is 2954 base pairs in length, encoding a protein of 458 amino acids, and shows high expression in tissues such as the lung, spleen, testis, and peripheral blood leukocytes. Genetic studies have highlighted its potential role in developmental disorders, such as global developmental delay and delayed speech and language development, linked to microdeletions encompassing the GTDC1 gene. Disruption of GTDC1 expression has been shown to affect neural progenitor cells and neurons, indicating its significance in neural development. Additionally, the gene holds evolutionary conservation, sharing 75% and 37% identity with its mouse and fruit fly counterparts, respectively.

Specifications

• Antigen: GTDC1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GTDC1
• Gene Alias: E330008O22Rik; glycosyltransferase like domain containing 1; glycosyltransferase-like 1; glycosyltransferase-like domain containing 1; glycosyltransferase-like domain-containing protein 1; glycosyltransferase-like protein; Gtdc1; Hmat-Xa; mannosyltransferase candidate; mannosyltransferase-like protein Xa; mat-Xa
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 79712
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q4AE62
• Gene Symbols: GTDC1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human GTDC1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov