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Invitrogen™ GTDC1 Polyclonal Antibody
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Catalog No. PIPA531858
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100 μL
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PIPA531858 100 μL
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Catalog No. PIPA531858 Supplier Invitrogen™ Supplier No. PA531858
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, Jurkat, Raji. Predicted reactivity: Mouse (93%), Xenopus laevis (81%), Chicken (85%), Rhesus Monkey (97%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The GTDC1 (Glycosyltransferase-Like Domain Containing 1) gene encodes a protein that is hypothesized to function as a glycosyltransferase. This gene has been implicated in several crucial biological processes, particularly in the nervous system. The GTDC1 cDNA is 2954 base pairs in length, encoding a protein of 458 amino acids, and shows high expression in tissues such as the lung, spleen, testis, and peripheral blood leukocytes. Genetic studies have highlighted its potential role in developmental disorders, such as global developmental delay and delayed speech and language development, linked to microdeletions encompassing the GTDC1 gene. Disruption of GTDC1 expression has been shown to affect neural progenitor cells and neurons, indicating its significance in neural development. Additionally, the gene holds evolutionary conservation, sharing 75% and 37% identity with its mouse and fruit fly counterparts, respectively.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GTDC1
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene GTDC1
Gene Accession No. Q4AE62
Gene Alias E330008O22Rik; glycosyltransferase like domain containing 1; glycosyltransferase-like 1; glycosyltransferase-like domain containing 1; glycosyltransferase-like domain-containing protein 1; glycosyltransferase-like protein; Gtdc1; Hmat-Xa; mannosyltransferase candidate; mannosyltransferase-like protein Xa; mat-Xa
Gene Symbols GTDC1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human GTDC1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79712
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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