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GTF2F1 Mouse anti-Human, Clone: OTI1D5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525660

Catalog No. PIMA525660


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Description

Description

In eukaryotic systems, initiation of transcription from protein-coding genes is a complex process requiring RNA polymerase II and broad families of auxiliary transcription factors. Such factors can be divided into two major functional classes: the basal factors that are required for transcription of all Pol II genes, including TFIIA, TFIIB, TFIID, TFIIE, TFIIF and TFIIH; and sequence-specific factors that regulate gene expression. The basal transcription factors and Pol II form a specific multiprotein complex near the transcription start site by interacting with core promotor elements such as the TATA box generally located 25-30 base pairs upstream of the transcription start site. TFIIF, a heteromer composed of a small (RAP 30) and a large (RAP 74) subunit, is required for RNA polymerase II to assemble into a preinitiation complex formed by promotor DNA and the general factors TFIID, IIA and IIB. In addition, TFIIF stimulates transcription elongation by RNA polymerase II.
Specifications

Specifications

GTF2F1
Monoclonal
0.88 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P35269
BTF4; C76800; General transcription factor IIF 74 kDa subunit; General transcription factor IIF subunit 1; General transcription factor IIF, polypeptide 1, 74kDa; Gtf2f1; MGC94148; OTTHUMP00000237859; RAP74; T2FA_HUMAN; TF2F1; TFIIF; TFIIF-alpha; Transcription initiation factor IIF subunit alpha; Transcription initiation factor RAP74;
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
2962
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot
OTI1D5
Unconjugated
GTF2F1
Liquid
GTF2F1
Full length human recombit protein of GTF2F1 produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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