GTF2H1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-6080	150 μL

Catalog No. 50-172-6080 Supplier Proteintech Group Inc Supplier No. 101731AP150UL

Description

Rabbit Polyclonal Antibody

TFIIH, a multisubunit complex is involved in several biological fundamental mechanisms of the cell: transcription, nucleotide excision repair and cell cycle regulation. p62 is one of the six subunits that constitutes the core of TFIIH. Analysis of the expression of the p62 gene reveals an over expression in testis tissue. This subunit of TFIIH participates in a variety of protein interactions. For example, Rb competes with TBP and p62 for binding to E2F thus repressing E2F mediated transactivation; herpes simplex virus VP16 and human p53, directly interact with the p62 subunit of TFIIH. In addition, TFIIH, via p62 phosphorylation is the major target for mitotic inactivation of transcription. GTF2H1 is a component of the core GTF2H basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. GTF2H1 is one of the six subunits forming the core GTF2H basal transcription factor.

Specifications

• Antigen: GTF2H1
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 0.5 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene: GTF2H1
• Gene Accession No.: P32780, Q9DBA9
• Gene Alias: BTF2, BTF2 p62, GTF2H1, TFB1, TFIIH
• Gene Symbols: Gtf2h1
• Host Species: Rabbit
• Immunogen: GTF2H1 Fusion Protein Ag0229
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 14884, 2965
• Target Species: Human, Mouse
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG