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Invitrogen™ GTF2H2 Polyclonal Antibody
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Catalog No. PIPA565462
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100 μL
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PIPA565462 100 μL
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Catalog No. PIPA565462 Supplier Invitrogen™ Supplier No. PA565462
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: HVSPPPASSSS ECSLIRMGFP QHTIASLSDQ DAKPSFSMAH LDGNTEPGLT LGGYFCPQCR AKYCELPVEC KICG Highest antigen sequence identity to the following orthologs - mouse 97%, rat 96%.

Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFII. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GTF2H2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Gtf2h2
Gene Accession No. Q13888
Gene Alias 44kDa; basal transcription factor 2, p44 subunit; basic transcription factor 2 44 kDa subunit; BTF2; BTF2 p44; BTF2P44; BTF2-p44; general transcription factor II H, polypeptide 2; general transcription factor II H, polypeptide 2 (44 kDa subunit); general transcription factor IIH polypeptide 2; General transcription factor IIH subunit 2; general transcription factor IIH, polypeptide 2; general transcription factor IIH, polypeptide 2 (44 kDa subunit); general transcription factor IIH, polypeptide 2, 44kD subunit; general transcription factor IIH, polypeptide 2, 44kDa; Gtf2h2; p44; T-BTF2P44; TFIIH; TFIIH basal transcription factor complex p44 subunit
Gene Symbols Gtf2h2
Host Species Rabbit
Immunogen Recombinant Human GTF2H2. Recombinant protein control fragment (Product #RP-104829).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2966
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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