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Invitrogen™ GTF2H2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5101163

Catalog No. PIPA5101163


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Description

Description

Antibody detects endogenous levels of total TF2H2.

Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFII. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

GTF2H2
Polyclonal
Unconjugated
Gtf2h2
44kDa; basal transcription factor 2, p44 subunit; basic transcription factor 2 44 kDa subunit; BTF2; BTF2 p44; BTF2P44; BTF2-p44; general transcription factor II H, polypeptide 2; general transcription factor II H, polypeptide 2 (44 kDa subunit); general transcription factor IIH polypeptide 2; General transcription factor IIH subunit 2; general transcription factor IIH, polypeptide 2; general transcription factor IIH, polypeptide 2 (44 kDa subunit); general transcription factor IIH, polypeptide 2, 44kD subunit; general transcription factor IIH, polypeptide 2, 44kDa; Gtf2h2; p44; T-BTF2P44; TFIIH; TFIIH basal transcription factor complex p44 subunit
Rabbit
Affinity Chromatography
RUO
23894, 294693, 2966
-20°C
Liquid
Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
A0JN27, Q13888, Q9JIB4
Gtf2h2
A synthesized peptide derived from human GTF2H2(Accession Q13888), corresponding to amino acid residues M1-E48.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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