Invitrogen™ GTF2IRD1 Polyclonal Antibody

Catalog No.	Quantity
PIPA578295	100 μL

Catalog No. PIPA578295 Supplier Invitrogen™ Supplier No. PA578295

Description

Rabbit Polyclonal Antibody

Positive Control: HeLa, HeLa nuclear Predicted Reactivity: Mouse (85%), Rat (85%), Rhesus Monkey (99%), Bovine (90%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Williams-Beuren syndrome (WBS) is a developmental disorder caused by the hemizygous microdeletion on chromosome 7q11.23. WBS is an autosomal dominant genetic condition that is characterized by physical, cognitive and behavioral traits. The physical traits associated with WBS include facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies and neurologic and musculoskeletal abnormalities. Mild retardation, a weakness in visual-spatial skills, anxiety and a short attention span are typical cognitive and behavioral traits of WBS patients. The WBSCR11 gene is located within the WBS deletion and may contribute to the developmental symptoms found in WBS because of a loss of the encoded transcription factor. WBSCR11 is also designated GRF2IRD1, GTF3, Cream1 and MusTRD1 in human and BEN in mouse, due to slight differences in gene structure. WBSCR11 is expressed in all adult tissues as several variants and has discrete spatial and temporal expression during embryogenesis.

Specifications

• Antigen: GTF2IRD1
• Applications: Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 0.12 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene: GTF2IRD1
• Gene Accession No.: Q9UHL9
• Gene Alias: 1700012P16Rik; Alb/c-myc line 166.8; Alb-c-myc line 166.8; BEN; Binding factor for early enhancer; c-myc line 166.8; CREAM1; ESTM9; general transcription factor 3; general transcription factor II I repeat domain-containing 1; General transcription factor III; general transcription factor II-I repeat domain-containing protein 1; GTF2I repeat domain containing 1; GTF2I repeat domain-containing 1; GTF2I repeat domain-containing protein 1; Gtf2il; Gtf2ird1; GTF3; hMusTRD1alpha1; Muscle TFII-I repeat domain-containing protein 1; muscle TFII-I repeat domain-containing protein 1 alpha 1; MUSTRD1; MusTRD1/BEN; RBAP2; slow-muscle-fiber enhancer-binding protein; Tg(Alb1-Myc)166.8Sst; transcription factor GTF3 alpha 2; transcription factor GTF3 gamma 2; USE B1-binding protein; WBS; WBSCR11; WBSCR12; Williams-Beuren syndrome chromosomal region 11 protein; Williams-Beuren syndrome chromosomal region 12 protein; Williams-Beuren syndrome chromosome region 11; X83320
• Gene Symbols: GTF2IRD1
• Host Species: Rabbit
• Immunogen: Recombinant protein encompassing a sequence within the center region of human GTF2IRD1. The exact sequence is proprietary.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 9569
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov