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Invitrogen™ GTPBP2 Polyclonal Antibody
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Catalog No. PIPA531995
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100 μL
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PIPA531995 100 μL
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Catalog No. PIPA531995 Supplier Invitrogen™ Supplier No. PA531995
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: 293T. Predicted reactivity: Mouse (99%), Rat (100%), Zebrafish (87%), Xenopus laevis (94%), Rhesus Monkey (100%), Bovine (98%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Small G proteins act as molecular switches for regulation of variety of cellular processes, such as nuclear transport, signal transduction, membrane trafficking and protein synthesis. GTPBP2 (GTP-binding protein 2) is a 602 amino acid G protein that is expressed in kidney, skeletal muscle, testis, brain and thymus, though it is not detected in liver. Expression of GTPBP2 is enhanced by ©-interferon stimulation in HeLa cells, THP-1 cells and thioglycollate-elicited mouse peritoneal macrophages. There are four isoforms of GTPBP2 that are expressed as a result of alternative splicing events. Since mutation of the gene encoding GTPBP1 does not lead to any phenotypic abnormalities, it is thought that there may be a genetic redundancy to make up for GTPBP1 lack-of-function. GTPBP2 shares 44% sequence similarity with GTPBP1 and also overlaps in expression pattern, suggesting that the GTPBP2 gene may compensate for GTPBP1 genetic abnormalities.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GTPBP2
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Gtpbp2
Gene Accession No. Q9BX10
Gene Alias GTP binding protein 2; GTP-binding protein 2; GTP-binding-like protein 2; gtpbp2; I79_024595; nmf205
Gene Symbols Gtpbp2
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human GTPBP2. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54676
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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