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GTPBP4 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501564342
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50-156-4342 20 μL
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Catalog No. 50-156-4342 Supplier Bethyl Laboratories, Inc Supplier No. A303132AT
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Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat

GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. ′Active′ in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.

Specifications

Antigen GTPBP4
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene GTPBP4
Gene Accession No. Q9BZE4
Gene Alias CRFG, NGB, NOG1, G protein-binding protein CRFG, GTP-binding protein NGB, chronic renal failure gene protein, nucleolar GTP-binding protein 1
Gene Symbols GTPBP4
Host Species Rabbit
Immunogen Between 200 and 250
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23560
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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