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Invitrogen™ GTPBP4 Recombinant Rabbit Monoclonal Antibody (JE47-47)
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Catalog No. PIMA534853
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100 μL
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PIMA534853 100 μL
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Catalog No. PIMA534853 Supplier Invitrogen™ Supplier No. MA534853
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Control: 293T cell, human liver cancer tissue, human thyroid gland tissue, human skin tissue, human breast tissue, thp-1.

GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GTPBP4
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone JE47-47
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene Gtpbp4
Gene Accession No. Q9BZE4
Gene Alias 2610028C09Rik; chronic renal failure gene protein; chronic renal failure protein; Crfg; fi28d07; FLJ10686; FLJ10690; FLJ39774; G protein-binding protein CRFG; GTP binding protein 3; GTP binding protein 4; GTP binding protein NGB; GTP-binding protein NGB; Gtpbp3; Gtpbp4; NGB; Nog1; nucleolar GTP-binding protein 1; Nucleolar GTP-binding protein 1 (Chronic renal failure gene protein) (GTP-binding protein NGB); Unknown (protein for IMAGE:7956347); wu:fi28d07; zgc:55757
Gene Symbols Gtpbp4
Host Species Rabbit
Immunogen Recombinant protein within Human GTPBP4 aa 1-131.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23560
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles, store in dark
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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