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Alfa Aesar™ Guanidine hydrochloride, Molecular Biology Grade

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Quantity:
100g
500g
50-01-1
CH6ClN3
95.53
MFCD00013026
PJJJBBJSCAKJQF-UHFFFAOYSA-N
guanidine hydrochloride,guanidinium chloride,guanidine, monohydrochloride,aminoformamidine hydrochloride,aminomethanamidine hydrochloride,guanidine monohydrochloride,guanidine hcl,guanidine chloride,iminourea hydrochloride,carbamidine hydrochloride
5742
CHEBI:32735
guanidine;hydrochloride
C(=N)(N)N.Cl
50-01-1
CH6ClN3
95.53
MFCD00013026
PJJJBBJSCAKJQF-UHFFFAOYSA-N
guanidine hydrochloride,guanidinium chloride,guanidine, monohydrochloride,aminoformamidine hydrochloride,aminomethanamidine hydrochloride,guanidine monohydrochloride,guanidine hcl,guanidine chloride,iminourea hydrochloride,carbamidine hydrochloride
5742
CHEBI:32735
guanidine;hydrochloride
C(=N)(N)N.Cl

A protein denaturant

Applications
Guanidine hydrochloride is used for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Guanidine hydrochloride is used in RNA isolation to dissociate nucleoproteins and inhibit RNase.

Solubility
Freely soluble in water

Notes
Protect from heat. Store away from oxidizing agents.
Density 1.34
Melting Point 178°C to 185°C
Color White
Sensitivity Hygroscopic
Quantity 100g
Beilstein 3591990
Merck Index 144562
Solubility Information Freely soluble in water
Formula Weight 95.53
Physical Form Crystalline Solid
Grade Molecular Biology
Chemical Name or Material Guanidine hydrochloride
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Causes serious eye irritation, May form combustible dust concentrations in air, Causes skin irritation, Harmful if swallowed or if inhaled

Serious eye damage/eye irritation (category 2), Skin corrosion/irritation (category 2), Acute toxicity (category 4)

EINECSNumber : 200-002-3

RTECSNumber : MF4300000

TSCA : Yes

Recommended Storage : Ambient temperatures

RMF - Research Use or Further Mfg