Alfa Aesar™ Guanidine hydrochloride, Molecular Biology Grade

Description

A protein denaturant

Applications
Guanidine hydrochloride is used for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary. Guanidine hydrochloride is used in RNA isolation to dissociate nucleoproteins and inhibit RNase.

Solubility
Freely soluble in water

Notes
Protect from heat. Store away from oxidizing agents.

Specifications

• Density: 1.34
• Melting Point: 178°C to 185°C
• Color: White
• Sensitivity: Hygroscopic
• Quantity: 100g
• Beilstein: 3591990
• Merck Index: 144562
• Solubility Information: Freely soluble in water
• Formula Weight: 95.53
• Physical Form: Crystalline Solid
• Grade: Molecular Biology
• Chemical Name or Material: Guanidine hydrochloride

Safety and Handling

Causes serious eye irritation, May form combustible dust concentrations in air, Causes skin irritation, Harmful if swallowed or if inhaled

Serious eye damage/eye irritation (category 2), Skin corrosion/irritation (category 2), Acute toxicity (category 4)

EINECSNumber : 200-002-3

RTECSNumber : MF4300000

TSCA : Yes

Recommended Storage : Ambient temperatures

SDS

RMF - Research Use or Further Mfg