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  5. Tocris Bioscience™ GW 501516

Tocris Bioscience™ GW 501516
GREENER_CHOICE

Catalog No. 567410
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Potent and selective PPARδ agonist

GW 501516 is a potent and selective PPARδ agonist (EC50 = 1.2 nM). Displays <1000-fold selectivity over other PPAR subtypes. Increases ABC A1 transporter expression and induces apolipoprotein A1-mediated cholesterol efflux in vitro. Also increase serum HDL cholesterol and lowers small, dense LDL levels in obesity in vivo models.

Specifications

Chemical Name or Material 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic acid
CAS 317318-70-0
Quantity 10 mg
Target PPAR delta Receptor Agonists
Molecular Formula C21H18F3NO3S2
Formula Weight 453.5
Purity >98%
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