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Tocris Bioscience™ GW 5074
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Quantity:
10 mg
50 mg
Description
GW 5074 is a potent, selective and cell-permeable c-Raf1 kinase inhibitor (IC50 = 9 nM). GW 5074 displays ≥ 100-fold selectivity for raf kinase over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. GW 5074 binds mutant huntingtin (mHTT) and decreases levels of mHTT in cultured hippocampal neurons and fibroblasts from patients with Huntington's disease. Brain penetrant.
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Specifications
Specifications
| Quantity | 10 mg |
| Formula Weight | 520.94 |
| Purity | >98% |
| Molecular Weight (g/mol) | 520.95 |
| Chemical Name or Material | GW 5074 |
Safety and Handling
| Recommended Storage | Desiccate at -20°C |
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