GYPA/GYPB Mouse anti-Human, Clone: HIR2, Abnova™

Catalog No.	Quantity
89-934-221	50 μg

Catalog No. 89-934-221 Supplier Abnova Corporation Supplier No. MAB12957

Description

Mouse monoclonal antibody raised against human GYPA/GYPB.

Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq]

Specifications

• Antigen: GYPA/GYPB
• Applications: Flow Cytometry, Immunohistochemistry (PFA fixed)
• Classification: Monoclonal
• Clone: HIR2
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against human GYPA/GYPB.
• Dilution: Flow Cytometry Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.2 (0.09% sodium azide).
• Gene Alias: CD235a/GPA/GPErik/GPSAT/GpMiIII/HGpMiIII/HGpMiV/HGpMiX/HGpMiXI/HGpSta(C)/MN/MNS
• Gene Symbols: GYPA
• Host Species: Mouse
• Immunogen: Human peripheral blood mononuclear cell (PBMC).
• Purification Method: Protein G purification
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2993/2994
• Target Species: Human
• Content And Storage: Store at 4°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2b