Invitrogen™ GZF1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA534375

Catalog No. PIPA534375

Description

A suggested positive control is human heart tissue lysate. PA5-34375 can be used with blocking peptide PEP-1418.

The GDNF-inducible zinc finger protein 1 (GZF1) is a sequence-specific transcriptional repressor with a BTB/POZ domain and ten zinc finger motifs whose expression is required for renal branching morphogenesis during kidney development. GZF1 binds to the 5'regulatory region of the homeodomain protein HOXA10, suggesting that GZF1 may play a role in morphogenesis other than kidney development. Recent experiments have indicated that GZF1 associates with nucleolin and this association is mediated by the first four zinc finger motifs of GZF1. It is thought that Nucleolin modulates the subcellular localization of GZF1 as well as its transcriptional repressor activity.

Specifications

• Antigen: GZF1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GZF1
• Gene Alias: GDNF inducible zinc finger protein 1; GDNF-inducible zinc finger protein 1; GZF1; ZBTB23; Zinc finger and BTB domain-containing protein 23; zinc finger protein 336; ZNF336
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64412
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q9H116
• Gene Symbols: GZF1
• Immunogen: An 18 amino acid synthetic peptide near the carboxy terminus of human GZF1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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