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  6. H-2D[d] Mouse anti-Mouse, FITC, Clone: 34-2-12, BD

H-2D[d] Mouse anti-Mouse, FITC, Clone: 34-2-12, BD

Catalog No. BDB562001 Shop All BD Biosciences Products
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BDB562001 50 μg
BDB553579 0.5 mg
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Catalog No. BDB562001 Supplier BD Biosciences Supplier No. 562001
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Description

Mouse Monoclonal Antibody

The 34-2-12 antibody (also known as 34-2-12S) recognizes the α3 domain of the H-2D[d]. The binding of the antibody to its epitope is independent of the α1 and α2 domains and β2 microglobulin. It cross-reacts with cells of the C3H.LG/Ckc strain. Reactivity with other haplotypes (eg, b, f, k, p, q, r, s) has not been observed. Soluble mAb 34-2-12 blocks binding of the Ly-49A-expressing T lymphoma EL4 to immobilized H-2D[d]. However, further studies utilizing this mAb indicate that the α3 domain is not involved in the interaction between Ly-49A, or Ly-49G2, and H-2D[d].

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

TRUSTED_SUSTAINABILITY

Specifications

Antigen H-2D[d]
Applications Flow Cytometry
Classification Monoclonal
Clone 34-2-12
Concentration 0.5mg/mL
Conjugate FITC
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen (C57BL/6 x DBA/2)F1 mouse splenocytes
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG2a κ
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For Research Use Only.

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