Invitrogen™ H-2Ld Monoclonal Antibody (30-5-7S), FITC

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA518006

Catalog No. PIMA518006

Description

MA5-18006 targets H-2Ld in CT and FACS applications and shows reactivity with Mouse samples. The MA5-18006 immunogen is mouse H-2Ld (public determinant H-2.65).

MHC Class I (H-2Ld) is a protein complex located on the surface of cells in vertebrates. Its main function is to present peptides derived from intracellular proteins to T cells for immune recognition. The structure of MHC Class I (H-2Ld) consists of a heavy chain, beta-2 microglobulin, and a peptide-binding groove that interacts with antigenic peptides. The location of MHC Class I (H-2Ld) varies depending on the cell type, but it is typically found on the surface of nucleated cells. HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Specifications

• Antigen: H-2Ld
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 4-5mg/mL BSA and 0.02% sodium azide
• Gene Accession No.: P01897
• Gene Symbols: H2-L
• Immunogen: mouse H-2Ld (public determinant H-2.65).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry
• Clone: 30-5-7S
• Conjugate: FITC
• Gene: H2-L
• Gene Alias: H2L; H-2L; H2-L; H2LD; histocompatibility 2, D region locus L; histocompatibility 2, L region
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 14980
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.
• Form: Liquid