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  5. Tocris Bioscience™ H-7 dihydrochloride

Tocris Bioscience™ H-7 dihydrochloride
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Catalog No. 054250
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Catalog No. Quantity
05-425-0 50 mg
05-421-0 10 mg
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Catalog No. 05-425-0 Supplier Tocris Bioscience™ Supplier No. 0542/50
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Description

Protein kinase inhibitor

H-7 dihydrochloride is a protein kinase inhibitor (IC50 values for inhibition of PKA, PKG, PKC and myosin light chain kinase are 3.0, 5.8, 6.0 and 97.0 μM, respectively. H-7 shows antiviral activity against influenza A (IC50 = 10 μM) in vitro. H-7 also inhibits interleukin-stimulated secretion of IgM and blocks PMA -stimulated interleukin 1β production.

Specifications

Chemical Name or Material '±-1-(5-Isoquinolinesulphonyl)-2-methylpiperazine dihydrochloride
CAS 108930-17-2
Assay Percent Range >99%
Quantity 50 mg
Solubility Soluble to 20mM in DMSO
Molecular Formula C14H17N3O2S.2HCl
Formula Weight Observed MW: 364.29

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