Invitrogen™ H-cadherin Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA547472

Catalog No. PIPA547472

Description

In direct ELISAs, approximately 100% cross-reactivity with recombinant mouse Cadherin-13 is observed, and less than 10% cross-reactivity with recombinant human (rh) N-Cadherin is observed, and less than 2% cross-reactivity with rhCadherin-8, rhCadherin-11, rhCadherin-17, rhE-Cadherin, rhP-Cadherin, rhVE-Cadherin and rhR-Cadherin is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

The protein encoded by this gene has a C-terminal domain with tRNA 3 processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: H-cadherin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDH13
• Gene Alias: 4932416G01Rik; CAD13; cadherin 13; cadherin 13, H-cadherin (heart); cadherin-13; CD39 antigen-like 3; CD39L3; CD39-like 3; CDH13; CDHH; Cdht; ecto-apyrase 3; ecto-ATPase 3; ecto-ATPDase 3; HB6; H-cadherin; H-cadherin (heart); heart cadherin; heart-cadherin; NTPDase 3; NTPDase-3; P105; T cad; T Cadherin; Tcad; T-cad; T-cadherin; Truncated cadherin; truncated-cadherin
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1012
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative; pH 7.4
• Gene Accession No.: P55290
• Gene Symbols: CDH13
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Cadherin-13 Glu23-Ala692.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG