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Tocris™ H10
SDP

Catalog No. 62281 Shop All Novus Biologicals Products
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62-281 1 mg
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Catalog No. 62-281 Supplier Tocris™ Supplier No. 6228/1

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Description

PARP14 inhibitor; cell-permeable

H10 is a pARP14 inhibitor (IC50 = 490 nM). Exhibits ~ 24- and 18-fold selectivity for PARP14 over PARP1 and TNKS1, respectively. Binds both the nicotinamide and adenine sites on PARP14. Inhibits PARP14 and induces apoptosis in HepG2 and RPMI-8226 in cancer cells in vitro.

Specifications

Chemical Name or Material 3-(N-(2-(4-(2-(4-((3-Carbamoylphenyl)amino)-4-oxobutanamido)ethyl)-1H-1,2,3-triazol-1-yl)ethyl)sulfamoyl)benzoic acid
CAS 2084811-68-5
Quantity 1 mg
Molecular Formula C24H27N7O7S
Formula Weight 557.58
Product Type Inhibitor
Purity 98%
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