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Invitrogen™ H2A.Zac pan-acetyl (K4,K7,K11,K13) Polyclonal Antibody
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Catalog No. PIPA5114690
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100 μL
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PIPA5114690 100 μL
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Catalog No. PIPA5114690 Supplier Invitrogen™ Supplier No. PA5114690
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of Acetyl-H2A.Z only when acetylated at Lys4/7/11/13.

H2A.Zac pan-acetyl (K4,K7,K11,K13) is classified under histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division.
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Specifications

Antigen H2A.Zac pan-acetyl (K4,K7,K11,K13)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide
Gene H2AFZ
Gene Accession No. P0C0S5
Gene Alias H2A histone family member Z; H2A histone family, member Z; H2A.z; H2a.z-1; H2A/z; H2AFZ; H2az; H2AZ histone; histone H2A.Z
Gene Symbols H2AFZ
Host Species Rabbit
Immunogen A synthesized peptide derived from human H2AFZ(Accession P0C0S5), corresponding to amino acid residues M1-S21.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3015
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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