H2AFY2 Mouse anti-Human, Clone: OTI1E9, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF803388

Catalog No. 50-166-6466

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation.

Specifications

• Antigen: H2AFY2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: H2AFY2
• Gene Alias: macroH2A2
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55506
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI1E9
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q9P0M6
• Gene Symbols: H2AFY2
• Immunogen: Human recombit protein fragment corresponding to amino acids 2-261 of human H2AFY2 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b