Invitrogen™ H2AK119ub Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120597

Catalog No. PIPA5120597

Description

Positive test controls include: NIH/3T3, C6. Immunogen sequence: LPKKT.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Specifications

• Antigen: H2AK119ub
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H2ac1
• Gene Alias: H2ALys119ub; Hist1h2aa; histone cluster 1, H2aa; histone H2A type 4; Histone H2A, testis; testis-specific histone 2a; Th2a; Ubiquityl-Histone 2A K119; Ubiquityl-Histone 2A Lys119
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 24828
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.65 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: Q00728
• Gene Symbols: H2ac1
• Immunogen: A synthetic ubiquitinated peptide around K119 of human HIST1H2AB (NP_7344661).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Rat
• Product Type: Antibody
• Isotype: IgG