Invitrogen™ H2BK5ac Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5114691

Catalog No. PIPA5114691

Description

Antibody detects endogenous levels of Acetyl-H2B only when acetylated at Lys5.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.

Specifications

• Antigen: H2BK5ac
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: H2BW2
• Gene Alias: 2610022J01Rik; Acetyl-Histone H2; Acetyl-Histone H2B K5; Acetyl-Histone H2B Lys5; AV127319; bA317E16.3; dJ160A22.3; dJ193B12.2; dJ221C16.3; dJ221C16.6; dJ221C16.8; dJ97D16.4; GL105; H2B; H2B 291A; H2B 291B; H2b 613; H2B GL105; H2B histone family member M; H2B histone family member W testis-specific; H2B histone family member W, testis specific; H2B histone family, member A; H2B histone family, member B; H2B histone family, member C; H2B histone family, member D; H2B histone family, member E; H2B histone family, member F; H2B histone family, member J; H2B histone family, member K; H2B histone family, member L; H2B histone family, member M; H2B histone family, member N; H2B histone family, member Q; H2B histone family, member R; H2B histone family, member S; H2B histone family, member T; H2B histone family, member U, (testis-specific); H2B histone family, member W, testis-specific; H2B K; H2B type 12; H2B.1; H2B.1A; H2B.1B; H2B.2; H2B/a; H2B/b; H2B/c; H2B/d; H2B/e; H2B/f; H2B/g; H2B/h; H2B/I; H2B/j; H2B/k; H2B/l; H2B/n; H2B/q; H2B/r; H2B/S; H2b-143; h2B-221; H2b-291b; H2b-613; H2Bb; H2BC10; H2bc4; H2BC6; H2BC7; H2BC8; H2b-f; H2BFA; H2BFAiii; H2BFB; H2BFC; H2BFD; H2BFE; H2BFF; H2BFG; H2BFH; H2BFJ; H2BFK; H2BFL; H2BFM; H2BFN; H2BFQ; H2BFR; H2bfs; H2BFT; H2BFU; H2BFWT; H2BGL105; H2BJ; H2b-j; H2BK; H2BK12ac; H2BK15ac; H2BK5ac; H2b-l; H2BLys5ac; H2b-n; H2BQ; H2BS14; H2BS14p; HIRA-interacting protein 1; HIRA-interacting protein 2; HIRIP1; HIRIP2; Hist1h2ba; Hist1h2bb; HIST1H2BC; HIST1H2BD; Hist1h2be; Hist1h2bf; Hist1h2bg; HIST1H2BH; HIST1H2BI; HIST1H2BJ; HIST1H2BK; Hist1h2bl; Hist1h2bm; Hist1h2bn; HIST1H2BO; HIST1H3I; Hist2h2be; HIST2H2BF; Hist3h2bb; histone 1, H2ba; histone 1, H2bb; histone 1, H2bc; histone 1, H2bd; histone 1, H2bg; histone 1, H2bh; histone 1, H2bi; histone 1, H2bj; histone 1, H2bk; histone 1, H2bl; histone 1, H2bm; histone 1, H2bn; histone 1, H2bo; histone 2, H2be; Histone 2B; histone 3, H2bb; histone cluster 1, H2ba; histone cluster 1, H2bb; histone cluster 1, H2bc; histone cluster 1, H2bd; histone cluster 1, H2bg; histone cluster 1, H2bh; histone cluster 1, H2bi; histone cluster 1, H2bj; histone cluster 1, H2bk; histone cluster 1, H2bl; histone cluster 1, H2bm; histone cluster 1, H2bn; histone cluster 1, H2bo; histone cluster 2, H2be; histone cluster 2, H2bf; histone cluster 3, H2bb; histone family member; histone H2B; histone H2B type 1-A; Histone H2B type 1-B; histone H2B type 1-C/E/F/G/I; Histone H2B type 1-C/E/G; histone H2B type 1-D; Histone H2B type 1-F/J/L; histone H2B type 1-H; Histone H2B type 1-J; histone H2B type 1-K; Histone H2B type 1-L; histone H2B type 1-M; Histone H2B type 1-N; histone H2B type 1-O; Histone H2B type 2-E; histone H2B type 2-F; Histone H2B type 3-B; histone H2B type F-M; Histone H2B type F-S; histone H2B type F-S-like; histone H2B type W-T; Histone H2B, testis; Histone H2B.1; histone H2B.1 A; Histone H2B.1 B; histone H2B.2; Histone H2B.a; histone H2B.b; Histone H2B.c; histone H2B.d; Histone H2B.e; histone H2B.f; Histone H2B.g; Histone H2B.h; Histone H2B.I; Histone H2B.j; histone H2B.k; Histone H2B.l; histone H2B.n; Histone H2B.q; histone H2B.r; Histone H2B.s; histone H2B-GL105; LOC102724334; MGC125414; MGC125415; MGC125416; MGC9388; R74621; RP1-193B12.10; STBP; T25626; testis-specific histone 2b; testis-specific histone H2B; Th2b; TSH2B; TSH2B.1
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 102724334, 114483833, 128312, 158983, 24829, 255626, 286436, 291157, 3017, 3018, 319177, 319178, 319181, 319182, 319183, 319184, 319186, 319190, 361247, 440689, 68024, 680312, 691488, 8339, 8340, 8341, 8342, 8345, 8346, 8347, 8348, 8349, 85236, 8970
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide
• Gene Accession No.: A0A2R8Y619, O60814, P06899, P0C1H6, P10854, P23527, P33778, P57053, P58876, P62807, P70696, Q00729, Q16778, Q5QNW6, Q64475, Q64478, Q64524, Q6ZWY9, Q7Z2G1, Q8CGP1, Q8N257, Q93079, Q96A08, Q99877, Q99879, Q99880
• Gene Symbols: H2B, H2bc1, H2BC10, H2BC11, H2BC12, H2BC13, H2BC14, H2BC15, H2BC17, H2bc18, H2BC21, H2BC3, H2BC4, H2BC5, H2BC8, H2BC9, H2BE1, H2BU1, H2BW1, H2BW2, HIST1H2BA, HIST1H2BD, HIST1H2BJ, HIST1H2BM, HIST1H2BO, LOC102724334
• Immunogen: A synthesized peptide derived from human H2BFS(Accession P57053), corresponding to amino acid residues M1-G27.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov