Invitrogen™ H3.3 G34W oncohistone mutant Recombinant Superclonal™ Antibody (4HCLC)

Rabbit Recombinant Superclonal Antibody

Catalog Number	Mfr. No.	Quantity
71-282-8	Invitrogen™ 712828	100 μg

Description

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit Superclonal™ antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production. This antibody is predicted to react with Mouse, Rat, Bovine. Note: Formerly called Recombinant polyclonal antibody, this product is now rebranded as Recombinant Superclonal™ antibody. The physical product and the performance remain unchanged.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Specifications

• Antigen: H3.3 G34W oncohistone mutant
• Concentration: 0.5 mg/mL
• Applications: ChIP Assay, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Regulatory Status: RUO
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P84243
• Gene ID (Entrez): 3020, 3021
• Immunogen: Peptide corresponding to human H3.3 G34W [aa30-aa39].
• Product Type: Antibody

• Clone: 4HCLC
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Classification: Recombinant Superclonal
• Form: Liquid
• Isotype: IgG
• Target Species: Human
• Gene: H3-3A
• Gene Alias: H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3.3; H3.3 G34W; H3.3A; H3.3B; H3/g; H3-3A; H3-3B; H3B; H3F3; H3F3A; H3F3B; H3FT; H3G34W; H3t; Histone 3.3; Histone cluster 3; Histone H3; Histone H3.3; Histone H3.3 G34W; Histone H3.3G34W; PP781
• Gene Symbols: H3-3A, H3-3B
• Primary or Secondary: Primary
• Purification Method: Protein A