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Invitrogen™ H3F3A Polyclonal Antibody
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Catalog No. PIPA5102939
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PIPA5102939 100 μL
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Catalog No. PIPA5102939 Supplier Invitrogen™ Supplier No. PA5102939
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Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total H3F3A.

Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells. H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome. Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modification that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
TRUSTED_SUSTAINABILITY

Specifications

Antigen H3F3A
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene H3-3A
Gene Accession No. P84243
Gene Alias H3 histone, family 3A; H3.3A; H3.3B; H3/a; H3-3A; H3-3B; H3F3; H3F3A; H3F3B; Histone 3; Histone H3.3; PP781
Gene Symbols H3-3A
Host Species Rabbit
Immunogen A synthesized peptide derived from human H3F3A; H3F3B(Accession P84243), corresponding to amino acid residues T7-K57.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3020
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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